nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse

An evaluation of the APPswe/PS1dE9 transgenic AD mouse, presenting with the toxic Aβ1-42 deposition found in human AD, allowed us to characterize time-dependent changes in inflammatory and cholinergic markers present in AD. Astrogliosis was observed in cortex and hippocampus, with cellular loss occu...

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Detalles Bibliográficos
Autores principales: D’Angelo, Chiara, Costantini, Erica, Salvador, Nieves, Marchioni, Michele, Di Nicola, Marta, Greig, Nigel H., Reale, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102527/
https://www.ncbi.nlm.nih.gov/pubmed/33958667
http://dx.doi.org/10.1038/s41598-021-89139-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102527/
https://www.ncbi.nlm.nih.gov/pubmed/33958667
http://dx.doi.org/10.1038/s41598-021-89139-x

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