Regulation of amyloid-β levels by matrix metalloproteinase-2/9 (MMP2/9) in the media of lung cancer cells

In this study, we set out to identify regulators of intact amyloid-β40/42 (Aβ) levels in A549 (p53 wild-type) and H1299 (p53-null) lung cancer cell media. Higher Aβ levels were detected in the media of A549 than H1299 cells without or with treatment with 4-methylumbelliferone (4-MU) and/or the anti-...

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Detalles Bibliográficos
Autores principales: Dorandish, Sadaf, Williams, Asana, Atali, Sarah, Sendo, Sophia, Price, Deanna, Thompson, Colton, Guthrie, Jeffrey, Heyl, Deborah, Evans, Hedeel Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102533/
https://www.ncbi.nlm.nih.gov/pubmed/33958632
http://dx.doi.org/10.1038/s41598-021-88574-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102533/
https://www.ncbi.nlm.nih.gov/pubmed/33958632
http://dx.doi.org/10.1038/s41598-021-88574-0

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