Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1

A non-canonical PRC1 (PRC1.6) prevents precocious meiotic onset. Germ cells alleviate its negative effect by reducing their amount of MAX, a component of PRC1.6, as a prerequisite for their bona fide meiosis. Here, we found that germ cells produced Mga variant mRNA bearing a premature termination co...

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Detalles Bibliográficos
Autores principales: Kitamura, Yuka, Uranishi, Kousuke, Hirasaki, Masataka, Nishimoto, Masazumi, Suzuki, Ayumu, Okuda, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102552/
https://www.ncbi.nlm.nih.gov/pubmed/33958653
http://dx.doi.org/10.1038/s41598-021-89123-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102552/
https://www.ncbi.nlm.nih.gov/pubmed/33958653
http://dx.doi.org/10.1038/s41598-021-89123-5

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