Cargando…
Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1
A non-canonical PRC1 (PRC1.6) prevents precocious meiotic onset. Germ cells alleviate its negative effect by reducing their amount of MAX, a component of PRC1.6, as a prerequisite for their bona fide meiosis. Here, we found that germ cells produced Mga variant mRNA bearing a premature termination co...
Autores principales: | Kitamura, Yuka, Uranishi, Kousuke, Hirasaki, Masataka, Nishimoto, Masazumi, Suzuki, Ayumu, Okuda, Akihiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102552/ https://www.ncbi.nlm.nih.gov/pubmed/33958653 http://dx.doi.org/10.1038/s41598-021-89123-5 |
Ejemplares similares
-
Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD
por: Nishimoto, Masazumi, et al.
Publicado: (2019) -
Striking Similarity in the Gene Expression Levels of Individual Myc Module Members among ESCs, EpiSCs, and Partial iPSCs
por: Hirasaki, Masataka, et al.
Publicado: (2013) -
Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing
por: Mochizuki, Kentaro, et al.
Publicado: (2021) -
Forced Expression of Nanog or Esrrb Preserves the ESC Status in the Absence of Nucleostemin Expression
por: Katano, Miyuki, et al.
Publicado: (2015) -
MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6
por: Stielow, Bastian, et al.
Publicado: (2018)