Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice

Mitochondrial Ca(2+) regulates a wide range of cell processes, including morphogenesis, metabolism, excitotoxicity, and survival. In cochlear hair cells, the activation of mechano-electrical transduction and voltage-gated Ca(2+) channels result in a large influx of Ca(2+). The intracellular rise in...

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Detalles Bibliográficos
Autores principales: Manikandan, Mayakannan, Walker, Steven, Deshmukh, Aditi R., Perea, Elizabeth, Wang, Danqi, Alagramam, Kumar N., Stepanyan, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102556/
https://www.ncbi.nlm.nih.gov/pubmed/33958614
http://dx.doi.org/10.1038/s41598-021-88841-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102556/
https://www.ncbi.nlm.nih.gov/pubmed/33958614
http://dx.doi.org/10.1038/s41598-021-88841-0

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