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Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice
Mitochondrial Ca(2+) regulates a wide range of cell processes, including morphogenesis, metabolism, excitotoxicity, and survival. In cochlear hair cells, the activation of mechano-electrical transduction and voltage-gated Ca(2+) channels result in a large influx of Ca(2+). The intracellular rise in...
Autores principales: | Manikandan, Mayakannan, Walker, Steven, Deshmukh, Aditi R., Perea, Elizabeth, Wang, Danqi, Alagramam, Kumar N., Stepanyan, Ruben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102556/ https://www.ncbi.nlm.nih.gov/pubmed/33958614 http://dx.doi.org/10.1038/s41598-021-88841-0 |
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