DGG-100629 inhibits lung cancer growth by suppressing the NFATc1/DDIAS/STAT3 pathway

DNA damage-induced apoptosis suppressor (DDIAS) promotes the progression of lung cancer and hepatocellular carcinoma through the regulation of multiple pathways. We screened a chemical library for anticancer agent(s) capable of inhibiting DDIAS transcription. DGG-100629 was found to suppress lung ca...

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Detalles Bibliográficos
Autores principales: Im, Joo-Young, Kim, Bo-Kyung, Yoon, Sung-Hoon, Cho, Byoung Chul, Baek, Yu Mi, Kang, Mi-Jung, Kim, Nayeon, Gong, Young-Dae, Won, Misun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102629/
https://www.ncbi.nlm.nih.gov/pubmed/33859351
http://dx.doi.org/10.1038/s12276-021-00601-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102629/
https://www.ncbi.nlm.nih.gov/pubmed/33859351
http://dx.doi.org/10.1038/s12276-021-00601-2

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