Genetic deletion of the ghrelin receptor (GHSR) impairs growth and blunts endocrine response to fasting in Ghsr-IRES-Cre mice

OBJECTIVE: The orexigenic hormone ghrelin exerts its physiological effects by binding to and activating the growth hormone secretagogue receptor (GHSR). The recent development of a Ghsr-IRES-Cre knock-in mouse line has enabled to genetically access GHSR-expressing neurons. Inserting a Cre construct...

Descripción completa

Detalles Bibliográficos
Autores principales: Peris-Sampedro, Fiona, Stoltenborg, Iris, Le May, Marie V., Zigman, Jeffrey M., Adan, Roger A.H., Dickson, Suzanne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102639/
https://www.ncbi.nlm.nih.gov/pubmed/33798772
http://dx.doi.org/10.1016/j.molmet.2021.101223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102639/
https://www.ncbi.nlm.nih.gov/pubmed/33798772
http://dx.doi.org/10.1016/j.molmet.2021.101223

Ejemplares similares