Ghrelin Alleviates Intestinal Dysfunction in Sepsis Through the KLF4/MMP2 Regulatory Axis by Activating SIRT1

Intestinal barrier dysfunction is an important contributor to morbidity caused by sepsis. This study investigates the molecular mechanism by which Ghrelin affects intestinal dysfunction in rat model of sepsis. A rat model of sepsis was established by cecal ligation and puncture (CLP), revealing that...

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Detalles Bibliográficos
Autores principales: Li, Bin, Dou, Zhimin, Zhang, Lei, Zhu, Lei, Cao, Yongqiang, Yu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102724/
https://www.ncbi.nlm.nih.gov/pubmed/33968038
http://dx.doi.org/10.3389/fimmu.2021.646775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102724/
https://www.ncbi.nlm.nih.gov/pubmed/33968038
http://dx.doi.org/10.3389/fimmu.2021.646775

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