Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials

BACKGROUND: near-infrared photoimmunotherapy (NIR-PIT) is a cancer treatment that uses antibody-photoabsorber (IRDye700DX, IR700) conjugates (APCs) which bind to target cells and are photoactivated by NIR light inducing rapid necrotic cell death. NIR-PIT targeting human epidermal growth factor recep...

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Detalles Bibliográficos
Autores principales: Okada, Ryuhei, Furusawa, Aki, Vermeer, Daniel W., Inagaki, Fuyuki, Wakiyama, Hiroaki, Kato, Takuya, Nagaya, Tadanobu, Choyke, Peter L., Spanos, William C., Allen, Clint T., Kobayashi, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102756/
https://www.ncbi.nlm.nih.gov/pubmed/33933782
http://dx.doi.org/10.1016/j.ebiom.2021.103345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102756/
https://www.ncbi.nlm.nih.gov/pubmed/33933782
http://dx.doi.org/10.1016/j.ebiom.2021.103345

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