Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation–Mass Spectrometry Assays

TMPRSS2-ERG gene fusion, a molecular alteration found in nearly half of primary prostate cancer cases, has been intensively characterized at the transcript level. However limited studies have explored the molecular identity and function of the endogenous fusion at the protein level. Here, we develop...

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Detalles Bibliográficos
Autores principales: Fu, Zhiqiang, Rais, Yasmine, Bismar, Tarek A., Hyndman, M. Eric, Le, X. Chris, Drabovich, Andrei P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102805/
https://www.ncbi.nlm.nih.gov/pubmed/33771697
http://dx.doi.org/10.1016/j.mcpro.2021.100075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102805/
https://www.ncbi.nlm.nih.gov/pubmed/33771697
http://dx.doi.org/10.1016/j.mcpro.2021.100075

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