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Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120(JRFL)
Despite current pharmacological intervention strategies, patients with HIV still suffer from chronic inflammation. The nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the nervous and immune systems. In macrophages, activation of alpha7-nAChR (α7-nAChR) controls inflammat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102909/ https://www.ncbi.nlm.nih.gov/pubmed/33811859 http://dx.doi.org/10.1016/j.jbc.2021.100618 |