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Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120(JRFL)

Despite current pharmacological intervention strategies, patients with HIV still suffer from chronic inflammation. The nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the nervous and immune systems. In macrophages, activation of alpha7-nAChR (α7-nAChR) controls inflammat...

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Detalles Bibliográficos
Autores principales:	Ríos, Sonnieliz Cotto, Colón Sáez, José O., Quesada, Orestes, Figueroa, Katherine Quiroz, Lasalde Dominicci, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102909/ https://www.ncbi.nlm.nih.gov/pubmed/33811859 http://dx.doi.org/10.1016/j.jbc.2021.100618

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