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Suppression of hypoxia and inflammatory pathways by Phyllanthus niruri extract inhibits angiogenesis in DMBA-induced breast cancer mice

BACKGROUND AND PURPOSE: Angiogenesis has been one of the hallmarks of cancer. In recent years, Phyllanthus niruri extract (PNE) was reported to inhibit angiogenesis by decreasing the levels of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor-1α (HIF-1α) in breast cancer. Howeve...

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Detalles Bibliográficos
Autores principales: Ramadhani, Abu Hanifah, Ahkam, Ahmad Hafidul, Suharto, Aditya Ragil, Jatmiko, Yoga Dwi, Tsuboi, Hideo, Rifa’i, Muhaimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102930/
https://www.ncbi.nlm.nih.gov/pubmed/34084208
http://dx.doi.org/10.4103/1735-5362.310528