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The tryptic peptides of hemoglobin for diagnosis of type 2 diabetes mellitus using label-free and standard-free LC-ESI-DMRM

N-1-(deoxyfructosyl) valine of β-hemoglobin, commonly referred to as HbA1c, is the “gold standard” for clinical detection of diabetes. Instead of quantifying the full-length HbA1c glycated protein, in the present study, we proposed the peptide-based strategy to quantify the depletion of the tryptic...

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Detalles Bibliográficos
Autores principales: Hong, Jie, Xin, Shuchen, Min, Rui, Zhang, Yongqian, Deng, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102995/
https://www.ncbi.nlm.nih.gov/pubmed/33932868
http://dx.doi.org/10.1016/j.redox.2021.101985