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SEMMs: Somatically Engineered Mouse Models. A New Tool for In Vivo Disease Modeling for Basic and Translational Research

Most experimental oncology therapies fail during clinical development despite years of preclinical testing rationalizing their use. This begs the question of whether the current preclinical models used for evaluating oncology therapies adequately capture patient heterogeneity and response to therapy...

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Detalles Bibliográficos
Autores principales: Lima, Anthony, Maddalo, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103029/
https://www.ncbi.nlm.nih.gov/pubmed/33968774
http://dx.doi.org/10.3389/fonc.2021.667189