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Genetic Defects in DNAH2 Underlie Male Infertility With Multiple Morphological Abnormalities of the Sperm Flagella in Humans and Mice

Asthenozoospermia accounts for over 80% of primary male infertility cases. Reduced sperm motility in asthenozoospermic patients are often accompanied by teratozoospermia, or defective sperm morphology, with varying severity. Multiple morphological abnormalities of the flagella (MMAF) is one of the m...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Yeon, Nawaz, Shoaib, Choi, Jungmin, Wang, Huafeng, Hussain, Shabir, Nawaz, Mehboob, Lopez-Giraldez, Francesc, Jeong, Kyungjo, Dong, Weilai, Oh, Jong-Nam, Bilguvar, Kaya, Mane, Shrikant, Lee, Chang-Kyu, Bystroff, Christopher, Lifton, Richard P., Ahmad, Wasim, Chung, Jean-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103034/
https://www.ncbi.nlm.nih.gov/pubmed/33968937
http://dx.doi.org/10.3389/fcell.2021.662903