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Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer

Early relapse after platinum chemotherapy in epithelial ovarian cancer (EOC) portends poor survival. A‐priori identification of platinum resistance is therefore crucial to improve on standard first‐line carboplatin–paclitaxel treatment. The DNA repair pathway homologous recombination (HR) repairs pl...

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Detalles Bibliográficos
Autores principales: Hoppe, Michal M, Jaynes, Patrick, Wardyn, Joanna D, Upadhyayula, Sai Srinivas, Tan, Tuan Zea, Lie, Stefanus, Lim, Diana G Z, Pang, Brendan N K, Lim, Sherlly, P S Yeong, Joe, Karnezis, Anthony, Chiu, Derek S, Leung, Samuel, Huntsman, David G, Sedukhina, Anna S, Sato, Ko, Topp, Monique D, Scott, Clare L, Choi, Hyungwon, Patel, Naina R, Brown, Robert, Kaye, Stan B, Pitt, Jason J, Tan, David S P, Jeyasekharan, Anand D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103098/
https://www.ncbi.nlm.nih.gov/pubmed/33709473
http://dx.doi.org/10.15252/emmm.202013366