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CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance

Most genetic alterations that drive melanoma development and resistance to targeted therapy have been uncovered. In contrast, and despite their increasingly recognized contribution, little is known about the non‐genetic mechanisms that drive these processes. Here, we performed in vivo gain‐of‐functi...

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Detalles Bibliográficos
Autores principales: Gautron, Arthur, Bachelot, Laura, Aubry, Marc, Leclerc, Delphine, Quéméner, Anaïs M, Corre, Sébastien, Rambow, Florian, Paris, Anaïs, Tardif, Nina, Leclair, Héloïse M, Marin‐Bejar, Oskar, Coulouarn, Cédric, Marine, Jean‐Christophe, Galibert, Marie‐Dominique, Gilot, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103100/
https://www.ncbi.nlm.nih.gov/pubmed/33724679
http://dx.doi.org/10.15252/emmm.202013466