The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

The tumor microenvironment in brain metastases is characterized by high myeloid cell content associated with immune suppressive and cancer‐permissive functions. Moreover, brain metastases induce the recruitment of lymphocytes. Despite their presence, T‐cell‐directed therapies fail to elicit effectiv...

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Detalles Bibliográficos
Autores principales: Niesel, Katja, Schulz, Michael, Anthes, Julian, Alekseeva, Tijna, Macas, Jadranka, Salamero‐Boix, Anna, Möckl, Aylin, Oberwahrenbrock, Timm, Lolies, Marco, Stein, Stefan, Plate, Karl H, Reiss, Yvonne, Rödel, Franz, Sevenich, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103101/
https://www.ncbi.nlm.nih.gov/pubmed/33755340
http://dx.doi.org/10.15252/emmm.202013412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103101/
https://www.ncbi.nlm.nih.gov/pubmed/33755340
http://dx.doi.org/10.15252/emmm.202013412

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