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Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis
Concurrent use of simvastatin (SV) and Gardenia jasminoides J. Ellis (GJ) was adopted in patients with multi-morbidity, such as stroke rehabilitation patients with NASH. Although hepatotoxicity has been reported in both of them and NASH could alter the pharmacokinetics of drugs/herbs, the interactio...
Autores principales: | Li, Ziwei, Lyu, Yuanfeng, Zhao, Jiajia, Li, Dan, Lin, Zhixiu, To, Kenneth Kin Wah, Yan, Xiaoyu, Zuo, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103205/ https://www.ncbi.nlm.nih.gov/pubmed/33967756 http://dx.doi.org/10.3389/fphar.2021.622040 |
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