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Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis

Concurrent use of simvastatin (SV) and Gardenia jasminoides J. Ellis (GJ) was adopted in patients with multi-morbidity, such as stroke rehabilitation patients with NASH. Although hepatotoxicity has been reported in both of them and NASH could alter the pharmacokinetics of drugs/herbs, the interactio...

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Detalles Bibliográficos
Autores principales: Li, Ziwei, Lyu, Yuanfeng, Zhao, Jiajia, Li, Dan, Lin, Zhixiu, To, Kenneth Kin Wah, Yan, Xiaoyu, Zuo, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103205/
https://www.ncbi.nlm.nih.gov/pubmed/33967756
http://dx.doi.org/10.3389/fphar.2021.622040