Cargando…

Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos

Primary cilia are ubiquitous microtubule-based organelles that serve as signaling hubs for numerous developmental pathways, most notably the Hedgehog (Hh) pathway. Defects in the structure or function of primary cilia result in a class of diseases called ciliopathies. It is well known that primary c...

Descripción completa

Detalles Bibliográficos
Autores principales: Brooks, Evan C., Bonatto Paese, Christian Louis, Carroll, Anne H., Struve, Jaime N., Nagy, Nandor, Brugmann, Samantha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103285/
https://www.ncbi.nlm.nih.gov/pubmed/33805906
http://dx.doi.org/10.3390/jdb9020012