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Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos
Primary cilia are ubiquitous microtubule-based organelles that serve as signaling hubs for numerous developmental pathways, most notably the Hedgehog (Hh) pathway. Defects in the structure or function of primary cilia result in a class of diseases called ciliopathies. It is well known that primary c...
Autores principales: | Brooks, Evan C., Bonatto Paese, Christian Louis, Carroll, Anne H., Struve, Jaime N., Nagy, Nandor, Brugmann, Samantha A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103285/ https://www.ncbi.nlm.nih.gov/pubmed/33805906 http://dx.doi.org/10.3390/jdb9020012 |
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