Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids

Lymphatic delivery of a vaccine can be achieved using a dendritic cell (DC)-targeted delivery system that can cause DC to migrate to lymph nodes upon activation by an adjuvant. Here, we designed a mannose-modified cationic lipid nanoparticle (M-NP) to deliver the nucleic acid adjuvant, polyinosinic:...

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Detalles Bibliográficos
Autores principales: Kim, Dongyoon, Wu, Yina, Shim, Gayong, Oh, Yu-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103501/
https://www.ncbi.nlm.nih.gov/pubmed/33916667
http://dx.doi.org/10.3390/pharmaceutics13040490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103501/
https://www.ncbi.nlm.nih.gov/pubmed/33916667
http://dx.doi.org/10.3390/pharmaceutics13040490

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