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Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids
Lymphatic delivery of a vaccine can be achieved using a dendritic cell (DC)-targeted delivery system that can cause DC to migrate to lymph nodes upon activation by an adjuvant. Here, we designed a mannose-modified cationic lipid nanoparticle (M-NP) to deliver the nucleic acid adjuvant, polyinosinic:...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103501/ https://www.ncbi.nlm.nih.gov/pubmed/33916667 http://dx.doi.org/10.3390/pharmaceutics13040490 |