The Bacterial Genomic Context of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases Highlights an Emerging Threat to Public Health

Type B dihydrofolate reductase (dfrb) genes were identified following the introduction of trimethoprim in the 1960s. Although they intrinsically confer resistance to trimethoprim (TMP) that is orders of magnitude greater than through other mechanisms, the distribution and prevalence of these short (...

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Detalles Bibliográficos
Autores principales: Lemay-St-Denis, Claudèle, Diwan, Sarah-Slim, Pelletier, Joelle N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103504/
https://www.ncbi.nlm.nih.gov/pubmed/33924456
http://dx.doi.org/10.3390/antibiotics10040433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103504/
https://www.ncbi.nlm.nih.gov/pubmed/33924456
http://dx.doi.org/10.3390/antibiotics10040433

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