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Intrapatient comparisons of efficacy in a single-arm trial of entrectinib in tumour-agnostic indications
BACKGROUND: Entrectinib is a tropomyosin receptor kinase inhibitor approved for the treatment of neurotrophic tyrosine receptor kinase (NTRK) fusion-positive solid tumours based on single-arm trials. Traditional randomised clinical trials in rare cancers are not feasible; we conducted an intrapatien...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103537/ https://www.ncbi.nlm.nih.gov/pubmed/33676294 http://dx.doi.org/10.1016/j.esmoop.2021.100072 |