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Toxicology and Pharmacokinetics Study of Intradiscal Injection of Simvastatin in Rabbits

To test the pharmacokinetics and toxicology of whole organs and tissues after intradiscal injection of simvastatin in rabbits. To provide the information needed to support human clinical trials. Twelve male and twelve female rabbits were randomly divided into four groups: control group (0 mg/ml), lo...

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Detalles Bibliográficos
Autores principales: Huang, Xiaodong, He, Wei, Wang, Weiheng, Fan, Quanchun, Ye, Xiaojian, Wu, Zenghui, Lin, Chia-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103611/
https://www.ncbi.nlm.nih.gov/pubmed/33967746
http://dx.doi.org/10.3389/fphar.2021.582309