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Toxicology and Pharmacokinetics Study of Intradiscal Injection of Simvastatin in Rabbits
To test the pharmacokinetics and toxicology of whole organs and tissues after intradiscal injection of simvastatin in rabbits. To provide the information needed to support human clinical trials. Twelve male and twelve female rabbits were randomly divided into four groups: control group (0 mg/ml), lo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103611/ https://www.ncbi.nlm.nih.gov/pubmed/33967746 http://dx.doi.org/10.3389/fphar.2021.582309 |