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Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. A single infusion of mesenchymal stem cells (MSCs) delays disease progression by protecting motor neurons and restoring the blood-spinal cord barrier in the S...

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Detalles Bibliográficos
Autores principales: Magota, Hirotoshi, Sasaki, Masanori, Kataoka-Sasaki, Yuko, Oka, Shinichi, Ukai, Ryo, Kiyose, Ryo, Onodera, Rie, Kocsis, Jeffery D., Honmou, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103621/
https://www.ncbi.nlm.nih.gov/pubmed/33962678
http://dx.doi.org/10.1186/s13041-021-00787-6