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Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. A single infusion of mesenchymal stem cells (MSCs) delays disease progression by protecting motor neurons and restoring the blood-spinal cord barrier in the S...
Autores principales: | Magota, Hirotoshi, Sasaki, Masanori, Kataoka-Sasaki, Yuko, Oka, Shinichi, Ukai, Ryo, Kiyose, Ryo, Onodera, Rie, Kocsis, Jeffery D., Honmou, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103621/ https://www.ncbi.nlm.nih.gov/pubmed/33962678 http://dx.doi.org/10.1186/s13041-021-00787-6 |
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