Respiratory Syncytial Virus Activates Rab5a To Suppress IRF1-Dependent Lambda Interferon Production, Subverting the Antiviral Defense of Airway Epithelial Cells

The limited antiviral options and lack of an effective vaccine against human respiratory syncytial virus (RSV) highlight the need for a novel antiviral therapy. One alternative is to identify and target the host factors required for viral infection. Here, using RNA interference to knock down Rab pro...

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Detalles Bibliográficos
Autores principales: Mo, Shi, Tang, Wei, Xie, Jun, Chen, Sisi, Ren, Luo, Zang, Na, Xie, Xiaohong, Deng, Yu, Gao, Leiqiong, Liu, Enmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103688/
https://www.ncbi.nlm.nih.gov/pubmed/33504607
http://dx.doi.org/10.1128/JVI.02333-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103688/
https://www.ncbi.nlm.nih.gov/pubmed/33504607
http://dx.doi.org/10.1128/JVI.02333-20

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