Cargando…

Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high‐fat diet‐fed hyperglycemic rabbits

Macrophage apoptosis is a key contributor to the progression of atherosclerosis. Cyclophilin A, a monocyte secretory protein associated with the initiation of atherosclerosis has an inherent nuclease activity. This study reports the mechanism by which cyclophilin A causes apoptosis of macrophages an...

Descripción completa

Detalles Bibliográficos
Autores principales: Anandan, Vinitha, Thankayyan Retnabai, Santhosh Kumar, Jaleel, Abdul, Thulaseedharan, Thushara, Mullasari, Ajit, Pillai, M. Radhakrishna, Kartha, Cheranellore Chandrasekharan, Ramachandran, Surya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103716/
https://www.ncbi.nlm.nih.gov/pubmed/33977232
http://dx.doi.org/10.1096/fba.2020-00135