Inhibition of the HEG1–KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells

The transmembrane protein heart of glass1 (HEG1) directly binds to and recruits Krev interaction trapped protein 1 (KRIT1) to endothelial junctions to form the HEG1–KRIT1 protein complex that establishes and maintains junctional integrity. Genetic inactivation or knockdown of endothelial HEG1 or KRI...

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Detalles Bibliográficos
Autores principales: Lopez‐Ramirez, Miguel Alejandro, McCurdy, Sara, Li, Wenqing, Haynes, Mark K., Hale, Preston, Francisco, Karol, Oukoloff, Killian, Bautista, Matthew, Choi, Chelsea H.J., Sun, Hao, Gongol, Brendan, Shyy, John Y., Ballatore, Carlo, Sklar, Larry A., Gingras, Alexandre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103725/
https://www.ncbi.nlm.nih.gov/pubmed/33977234
http://dx.doi.org/10.1096/fba.2020-00141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103725/
https://www.ncbi.nlm.nih.gov/pubmed/33977234
http://dx.doi.org/10.1096/fba.2020-00141

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