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Double and single mixed-lineage leukemia-rearranged subclones in pediatric acute myeloid leukemia: a case report

BACKGROUND: Acute myeloid leukemia (AML) is a disease with a significant amount of cytogenetic heterogeneity including mixed-lineage leukemia (MLL) gene rearrangements. Pediatric AML commonly has genetic rearrangements which involve chromosome 11q23 in 15–20% of cases, and these genetic abnormalitie...

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Detalles Bibliográficos
Autores principales: McGrath, Mary, Smink, Gayle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103755/
https://www.ncbi.nlm.nih.gov/pubmed/33957966
http://dx.doi.org/10.1186/s13256-021-02841-2