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Double and single mixed-lineage leukemia-rearranged subclones in pediatric acute myeloid leukemia: a case report
BACKGROUND: Acute myeloid leukemia (AML) is a disease with a significant amount of cytogenetic heterogeneity including mixed-lineage leukemia (MLL) gene rearrangements. Pediatric AML commonly has genetic rearrangements which involve chromosome 11q23 in 15–20% of cases, and these genetic abnormalitie...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103755/ https://www.ncbi.nlm.nih.gov/pubmed/33957966 http://dx.doi.org/10.1186/s13256-021-02841-2 |