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Massively parallel and time-resolved RNA sequencing in single cells with scNT-Seq

Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-Seq), a method for massively parallel analysis of newly-transcribed and pre-existing mRNAs from the same cell...

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Detalles Bibliográficos
Autores principales: Qiu, Qi, Hu, Peng, Qiu, Xiaojie, Govek, Kiya W., Camara, Pablo G., Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103797/
https://www.ncbi.nlm.nih.gov/pubmed/32868927
http://dx.doi.org/10.1038/s41592-020-0935-4