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IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo

Mycobacterium tuberculosis infections claim more than a million lives each year, and better treatments or vaccines are required. A crucial pathogenicity factor is translocation from phagolysosomes to the cytosol upon phagocytosis by macrophages. Translocation from the phagolysosome to the cytosol is...

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Detalles Bibliográficos
Autores principales: van der Niet, Sanne, van Zon, Maaike, de Punder, Karin, Grootemaat, Anita, Rutten, Sofie, Moorlag, Simone J. C. F. M., Houben, Diane, van der Sar, Astrid M., Bitter, Wilbert, Brosch, Roland, Hernandez Pando, Rogelio, Pena, Maria T., Peters, Peter J., Reits, Eric A., Mayer-Barber, Katrin D., van der Wel, Nicole N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103984/
https://www.ncbi.nlm.nih.gov/pubmed/33952660
http://dx.doi.org/10.1128/mSphere.00153-21