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Development of a New Reverse Genetics System for Ebola Virus

Ebola virus (EBOV) is a highly pathogenic negative-stranded RNA virus that has caused several deadly endemics in the past decades. EBOV reverse genetics systems are available for studying live viruses under biosafety level 4 (BSL-4) or subviral particles under BSL-2 conditions. However, these system...

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Detalles Bibliográficos
Autores principales: Gan, Tianyu, Zhou, Dihan, Huang, Yi, Xiao, Shuqi, Ma, Ziyue, Hu, Xiaoyou, Tong, Yimin, Yan, Huimin, Zhong, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103987/
https://www.ncbi.nlm.nih.gov/pubmed/33952663
http://dx.doi.org/10.1128/mSphere.00235-21