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The NLRP3-Inflammasome-Caspase-1 Pathway Is Upregulated in Idiopathic Pulmonary Fibrosis and Acute Exacerbations and Is Inducible by Apoptotic A549 Cells

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive disease harboring significant morbidity and mortality despite recent advances in therapy. Regardless of disease severity acute exacerbations (IPF-AEs) may occur leading to considerable loss of function and are the leading cause of dea...

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Detalles Bibliográficos
Autores principales: Jäger, Benedikt, Seeliger, Benjamin, Terwolbeck, Oliver, Warnecke, Gregor, Welte, Tobias, Müller, Meike, Bode, Christian, Prasse, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104027/
https://www.ncbi.nlm.nih.gov/pubmed/33968032
http://dx.doi.org/10.3389/fimmu.2021.642855