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A Novel Antigenic Site Spanning Domains I and III of the Zika Virus Envelope Glycoprotein Is the Target of Strongly Neutralizing Human Monoclonal Antibodies

Zika virus (ZIKV), a mosquito-transmitted flavivirus, caused a large epidemic in Latin America between 2015 and 2017. Effective ZIKV vaccines and treatments are urgently needed to prevent future epidemics and severe disease sequelae. People infected with ZIKV develop strongly neutralizing antibodies...

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Detalles Bibliográficos
Autores principales: Graham, Stephen D., Tu, Huy A., McElvany, Benjamin D., Graham, Nancy R., Grinyo, Ariadna, Davidson, Edgar, Doranz, Benjamin J., Diehl, Sean A., de Silva, Aravinda M., Markmann, Alena Janda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104094/
https://www.ncbi.nlm.nih.gov/pubmed/33597214
http://dx.doi.org/10.1128/JVI.02423-20