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Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition

Negative-sense RNA viruses (NSVs) rely on prepackaged viral RNA-dependent RNA polymerases (RdRp) to replicate and transcribe their viral genomes. Their replication machinery consists of an RdRp bound to viral RNA which is wound around a nucleoprotein (NP) scaffold, forming a viral ribonucleoprotein...

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Detalles Bibliográficos
Autores principales:	Nilsson-Payant, Benjamin E., Blanco-Melo, Daniel, Uhl, Skyler, Escudero-Pérez, Beatriz, Olschewski, Silke, Thibault, Patricia, Panis, Maryline, Rosenthal, Maria, Muñoz-Fontela, César, Lee, Benhur, tenOever, Benjamin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Cellular Response to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104106/ https://www.ncbi.nlm.nih.gov/pubmed/33568513 http://dx.doi.org/10.1128/JVI.02274-20

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