MicroRNA-23a reduces lipopolysaccharide-induced cellular apoptosis and inflammatory cytokine production through Rho-associated kinase 1/sirtuin-1/nuclear factor-kappa B crosstalk

BACKGROUND: MicroRNAs are closely associated with the progression and outcomes of multiple human diseases, including sepsis. In this study, we examined the role of miR-23a in septic injury. METHODS: Lipopolysaccharide (LPS) was used to induce sepsis in a rat model and H9C2 and HK-2 cells. miR-23a ex...

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Detalles Bibliográficos
Autores principales: Shi, Xiao-Jun, Jin, Ye, Xu, Wei-Ming, Shen, Qing, Li, Jun, Chen, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104237/
https://www.ncbi.nlm.nih.gov/pubmed/33538509
http://dx.doi.org/10.1097/CM9.0000000000001369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104237/
https://www.ncbi.nlm.nih.gov/pubmed/33538509
http://dx.doi.org/10.1097/CM9.0000000000001369

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