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Caenorhabditis elegans PTR/PTCHD PTR-18 promotes the clearance of extracellular hedgehog-related protein via endocytosis

Spatiotemporal restriction of signaling plays a critical role in animal development and tissue homeostasis. All stem and progenitor cells in newly hatched C. elegans larvae are quiescent and capable of suspending their development until sufficient food is supplied. Here, we show that ptr-18, which e...

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Detalles Bibliográficos
Autores principales: Chiyoda, Hirohisa, Kume, Masahiko, del Castillo, Carla Cadena, Kontani, Kenji, Spang, Anne, Katada, Toshiaki, Fukuyama, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104386/
https://www.ncbi.nlm.nih.gov/pubmed/33872306
http://dx.doi.org/10.1371/journal.pgen.1009457