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Genome-wide DNA methylation and RNA-seq analyses identify genes and pathways associated with doxorubicin resistance in a canine diffuse large B-cell lymphoma cell line

Doxorubicin resistance is a major challenge in the successful treatment of canine diffuse large B-cell lymphoma (cDLBCL). In the present study, MethylCap-seq and RNA-seq were performed to characterize the genome-wide DNA methylation and differential gene expression patterns respectively in CLBL-1 8....

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Detalles Bibliográficos
Autores principales: Hsu, Chia-Hsin, Tomiyasu, Hirotaka, Liao, Chi-Hsun, Lin, Chen-Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104391/
https://www.ncbi.nlm.nih.gov/pubmed/33961622
http://dx.doi.org/10.1371/journal.pone.0250013