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The structure of MgtE in the absence of magnesium provides new insights into channel gating
MgtE is a Mg(2+) channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg(2+) homeostasis. The previously determined MgtE structures in the Mg(2+)-bound, closed-state, and structure-based functional analyses of MgtE revealed that the...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104411/ https://www.ncbi.nlm.nih.gov/pubmed/33905418 http://dx.doi.org/10.1371/journal.pbio.3001231 |