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Testcrosses are an efficient strategy for identifying cis-regulatory variation: Bayesian analysis of allele-specific expression (BayesASE)

Allelic imbalance (AI) occurs when alleles in a diploid individual are differentially expressed and indicates cis acting regulatory variation. What is the distribution of allelic effects in a natural population? Are all alleles the same? Are all alleles distinct? The approach described applies to an...

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Detalles Bibliográficos
Autores principales: Miller, Brecca R, Morse, Alison M, Borgert, Jacqueline E, Liu, Zihao, Sinclair, Kelsey, Gamble, Gavin, Zou, Fei, Newman, Jeremy R B, León-Novelo, Luis G, Marroni, Fabio, McIntyre, Lauren M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104932/
https://www.ncbi.nlm.nih.gov/pubmed/33772539
http://dx.doi.org/10.1093/g3journal/jkab096