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Ongoing repair of migration-coupled DNA damage allows planarian adult stem cells to reach wound sites

Mechanical stress during cell migration may be a previously unappreciated source of genome instability, but the extent to which this happens in any animal in vivo remains unknown. We consider an in vivo system where the adult stem cells of planarian flatworms are required to migrate to a distal woun...

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Detalles Bibliográficos
Autores principales: Sahu, Sounak, Sridhar, Divya, Abnave, Prasad, Kosaka, Noboyoshi, Dattani, Anish, Thompson, James M, Hill, Mark A, Aboobaker, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104965/
https://www.ncbi.nlm.nih.gov/pubmed/33890575
http://dx.doi.org/10.7554/eLife.63779