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Harnessing CRISPR-Cas9 for Genome Editing in Streptococcus pneumoniae D39V

CRISPR-Cas systems provide bacteria and archaea with adaptive immunity against viruses and plasmids by the detection and cleavage of invading foreign DNA. Modified versions of this system can be exploited as a biotechnological tool for precise genome editing at a targeted locus. Here, we developed a...

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Detalles Bibliográficos
Autores principales: Synefiaridou, Dimitra, Veening, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105017/
https://www.ncbi.nlm.nih.gov/pubmed/33397704
http://dx.doi.org/10.1128/AEM.02762-20