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Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma

High-risk neuroblastoma (NB) remains a significant therapeutic challenge facing current pediatric oncology patients. Structural variants such as gene fusions have shown an initial promise in enhancing mechanistic understanding of NB and improving survival rates. In this study, we performed a compreh...

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Detalles Bibliográficos
Autores principales: Liu, Zhichao, Chen, Xi, Roberts, Ruth, Huang, Ruili, Mikailov, Mike, Tong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105087/
https://www.ncbi.nlm.nih.gov/pubmed/33967751
http://dx.doi.org/10.3389/fphar.2021.608778