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Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma
High-risk neuroblastoma (NB) remains a significant therapeutic challenge facing current pediatric oncology patients. Structural variants such as gene fusions have shown an initial promise in enhancing mechanistic understanding of NB and improving survival rates. In this study, we performed a compreh...
Autores principales: | Liu, Zhichao, Chen, Xi, Roberts, Ruth, Huang, Ruili, Mikailov, Mike, Tong, Weida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105087/ https://www.ncbi.nlm.nih.gov/pubmed/33967751 http://dx.doi.org/10.3389/fphar.2021.608778 |
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